Fillers · Hyaluronidase
Hyaluronidase
Hyaluronidase is the enzyme that dissolves hyaluronic acid. It undoes a filler that was overdone, has migrated, has formed a lump or simply is not what you wanted. Done here or elsewhere. The effect starts within hours and is complete in a few days.

We dissolve what is needed and no more. A small dose removes a local excess; a larger dose dissolves everything. At the consultation we see where the product is, what you want to keep and whether it makes sense to refill afterwards. We do a skin test first, because of the rare risk of allergy.
The session takes 30 minutes. It costs €150.
What changes with hyaluronidase
An enzyme that breaks down hyaluronic acid. Injected in the right spot, it dissolves a filler within hours to days, fully or in part. It does not act on fillers made of other substances.
Is it for you?
A filler that was overdone, has migrated, has formed a lump or sits asymmetrically. A result you do not like, done here or at another clinic. Or a fresh start with a better plan.
What happens in the session
We see where the product is and set the dose. A skin test the first time, because of the rare risk of allergy. Numbing cream, then small injections in the area to dissolve. Thirty minutes.
What you'll see, and when
Within the first hours. The full effect takes 2 to 3 days. Reassessment at one week; if product remains, we repeat.
After the treatment
No massage or pressure on the area for the first 24 hours. No gym, sauna or alcohol for 48 hours. Light swelling for a day or two is normal.
Why it looks natural
Dissolving is a design decision too. A small dose removes a local excess; a larger one clears everything for a fresh start. We map where the product sits before injecting, dissolve what is needed and no more, and reassess at one week. The goal is the contour you had before the filler.
Honest answers
Will it show? What disappears is the filler: the difference starts within hours and is complete in 2 to 3 days, once the swelling settles.
Does it hurt? Numbing cream first. You feel a pinch and some warmth in the area, and light swelling can follow for 24 to 48 hours.
What if too much dissolves? The area's own hyaluronic acid rebuilds within weeks, and new filler is possible after 2 weeks. Many people dissolve precisely to start again with a better plan.
How we do it at Cosmo Clinic
We dissolve what is needed and no more. When the goal is to start again, the new lip filler or filler in another area is booked for 2 weeks later, plan already made. €150. The assessment consultation is free.
Options and prices
| Treatment | Price |
|---|---|
| Lip filler — 1 ml | 189 € |
| Dermal filler — 1 ml (chin, cheeks, jawline, temples, nasolabial, marionette, barcode) | 219 € |
| Under-eye filler | 328 € |
| Non-surgical rhinoplasty (rinofiller) | 368 € |
| Hyaluronidase (filler dissolving) | 150 € |
The plan and the final figure are confirmed at the assessment consultation, at no cost.
At a glance
What to expect
Results
- Excess, migration or lump of hyaluronic acid dissolved.
- The area's contour back to natural.
- Effect within hours; complete in a few days.
- New filler possible after 2 weeks.
Key features
- Acts only on hyaluronic acid; leaves other fillers alone.
- Partial or full dissolving, depending on the goal.
- Skin test first, 30-minute session.
- €150, price per treatment.
Frequently asked questions
Short answers to the questions we hear every day. Everything else belongs in the consultation.
When is it used?
When a filler is overdone, has migrated (a lip that "climbs" into the skin), has formed a lump, is asymmetrical or bluish, or when you simply do not like the result. And, rarely, in a vascular emergency, where it is the first-line treatment.
How fast does it work?
You see the difference within the first hours; the full effect takes 2 to 3 days. We reassess at one week and repeat if product remains.
Does it hurt?
You feel a pinch and some warmth in the area. Numbing cream first. Afterwards there may be swelling for 24 to 48 hours, which passes.
Does it dissolve any filler?
Only hyaluronic acid. Fillers made of other substances do not respond. If you do not know what you have, we tell you how to find out.
Can I have new filler afterwards?
Yes, after 2 weeks, once the enzyme is no longer active. Many people dissolve in order to start again with a better plan.
Do you dissolve filler done at another clinic?
Yes. It is a large part of what we do with hyaluronidase. We assess the area and what you know about the product, and set the dose.
Is it safe?
It is an enzyme used for decades. The risk to keep in mind is allergy, which is rare; that is why we do a skin test before the first application. It also dissolves some of the area's natural hyaluronic acid, which rebuilds within weeks.
What should I do afterwards?
No massage or pressure on the area for the first 24 hours. No gym, sauna or alcohol for 48 hours. Come back for the reassessment at one week.
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