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Hyaluronidase in Lisbon

€12030 min

Cosmo Clinic Team

Hyaluronidase is an enzyme that dissolves hyaluronic acid filler. In aesthetic medicine it is used to fully or partially reverse a filler treatment — whether because of overfilling, asymmetry, product migration, or simply a result you are not happy with.

At Cosmo Clinic in Lisbon, hyaluronidase is administered by licensed doctors after assessing the treated area and the filler history — including treatments performed at other clinics. The enzyme starts working within hours, and the final result is reviewed about two weeks later.

Your first consultation at Cosmo Clinic is free. Speak with one of our English-speaking doctors about your options before deciding on treatment.

Hyaluronidase filler dissolving at Cosmo Clinic Lisbon

Results

Correction of unwanted filler results.

Correction of unwanted filler results.

Natural contour of the treated area restored.

Natural contour of the treated area restored.

Filler dissolved within hours to days.

Filler dissolved within hours to days.

New filler possible after about 2 weeks.

New filler possible after about 2 weeks.

Key Features

Works only on hyaluronic acid fillers.
Full or partial dissolving, depending on your goal.
Quick treatment with minimal downtime.
Suitable for filler placed at other clinics.

Clinical Guide

Facial Fillers: Complete Guide

Zones, technique, recovery and contraindications.

Read the guide

FAQ

It is an enzyme that breaks down hyaluronic acid — the material used in most facial fillers. Injected into the treated area, it dissolves the filler in a controlled way, allowing a result to be corrected or reversed.

When a filler result is not what you wanted: overfilling, asymmetry, lumps, product migration, or simply a change of mind. Doctors also use it in clinical situations that require dissolving the product.

Discomfort is mild and brief. A topical numbing cream can be applied beforehand. Most patients describe it as a small pinch, similar to the original filler treatment.

The enzyme starts working within hours, with most of the dissolving happening in the first 48 hours. The final result is reviewed about two weeks later; a second session is sometimes needed.

No. It works only on hyaluronic acid fillers. Collagen biostimulators and other products are not dissolved by this enzyme. Your doctor confirms the product type at the consultation before proposing treatment.

Yes. After dissolving, we recommend waiting about two weeks before placing new filler, so the tissue settles and the result can be properly assessed.

Yes. Most hyaluronidase requests concern filler placed elsewhere. The doctor assesses the area, the product type, and the treatment history before defining a dissolving plan.

It is an established treatment in aesthetic medicine, performed at Cosmo Clinic by licensed doctors after a prior assessment. As with any injectable, temporary swelling or bruising can occur; allergic reactions are rare, and a medical assessment including your allergy history is always required.

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What is hyaluronidase

Hyaluronidase is an enzyme that breaks down hyaluronic acid — the material used in the vast majority of facial fillers. In aesthetic medicine it is the reference treatment for dissolving filler in a controlled way: fully, when you want to reverse a result completely, or partially, when only excess product or irregularities need correcting.

Who is it for

Suitable for adults with hyaluronic acid filler showing overfilling, asymmetry, visible lumps, or product migration — or who simply want to reverse the result. It applies to lip filler and filler in other facial areas, including treatments performed at other clinics. A prior medical consultation, including your allergy history, is always required.

What to expect from the session

Sessions run 15 to 30 minutes. After cleansing and disinfection, the doctor injects hyaluronidase precisely into the points where filler needs to be dissolved, using an ultra-fine needle. A topical numbing cream can be applied beforehand. The area is then gently massaged to distribute the enzyme.

Results timeline

The enzyme starts working within hours, with most of the dissolving happening in the first 48 hours. Mild swelling and occasional small bruising are normal during this period. The final result is reviewed around day 14; if needed, the doctor proposes a second session. New filler can be placed about two weeks after dissolving.

Aftercare

For 48 hours, avoid saunas, the gym, alcohol, and direct sun exposure, and do not massage the treated area. Topical arnica may be used to reduce any bruising, and sunscreen on the area is recommended for the following two weeks. You can return to your normal routine immediately.

Why Cosmo Clinic

Dissolving filler demands rigorous assessment and precise dosing — removing only what is needed while preserving your natural tissue. At Cosmo Clinic, Rua Filipe Folque 30 (Saldanha), treatment is always performed by licensed doctors, with consultations in Portuguese and English. After the correction, your doctor can propose a fresh plan, such as conservative lip filler or a skin booster for hydration. See all filler treatments available.

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Clinical Information

Responsible physician: Dr. Moria Andrade, Cédula No. 10810. Procedures performed by licensed medical professionals.

Clinic in Lisbon (Saldanha), registered with INFARMED. Your assessment is carried out with a specialist during a free initial consultation.

Results vary by individual. Meet the team on our About Us page.